Kidney Stones

Kidney stones (also called renal calculi, nephrolithiasis or urolithiasis) are hard deposits made of minerals and salts that form inside the kidneys. They can affect any part of the urinary tract from the kidneys to the urinary bladder; often the stones form when urine becomes concentrated, allowing minerals to cyrstallize and stick together.

The worldwide prevalence of kidney stones is 10% with an annual incidence of 1%. This prevalence has been increasing over the years. However, this prevalence is higher in hot, arid, or dry climates, such as mountains, desert, or tropical areas.

Prevalence of kidney stones is also directly correlated with type 2 diabetes, obesity, and variation measures of adiposity variables, including higher waist circumference, and BMI in both sexes.

Types of Kidney Stones.

Type of stone

Prevalence

Calcium Oxalate

80%

Calcium Phosphate

5-10%

Uric acid

5-10%

Struvite

10-15%

Cystine

1-2%

Management of Kidney Stones

  • MEDICAL TREATMENT (MEDICAL EXPULSIVE THERAPY)

Analgesics

Alpha-blockers

  • LIFESTYLE CHANGES
  • SURGERY
 GENERAL PREVENTATIVE MEASURES.
  • Fluid Intake
  • Nutritional advice for balanced diet.
  • Lifestyle advice to normalize general risk factors.

Recurrence of Kidney Stones

There is an increase in the risk for kidney stone for those patients who have had a previous episode. This has prompted the need for innovative scientific approach to developing a medical treatment to prevent the recurrence of kidney stones.

SiSi Pharmaceuticals together with Devicare Ltd have the breakthrough treatment for these types of patients in Kenya.

 TREATMENT CONCEPT

The combination of urine pH modulation with the inhibition of urinary crystallization. The pH modulation stops urine supersaturation while crystallization inhibitors arrest the crystallization process.

The products available are:

LIT-CONTROL pH balance for the prevention of the recurrence of calcium stones.

LIT-CONTROL pH up for the prevention of the recurrence of uric stones.